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The Trw Type IV Secretion System of Bartonella Mediates Host-Specific Adhesion to Erythrocytes

10 Jun 2010

Abstract excerpt

Bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood. The alpha-proteobacterial genus Bartonella comprises 21 species that cause host-specific intraerythrocytic bacteremia as hallmark of infection in their respective mammalian reservoirs, including the human-specific pathogens Bartonella quintana and Bartonella...

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PMID: 20548954
DOI: 10.1371/journal.ppat.1000946

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