Article
Neuropeptide Y receptor Y2 gene polymorphism interacts with plasma neuropeptide Y levels in predicting left ventricular hypertrophy in dialysis patients.
Journal of hypertension - 1 Aug 2010
Testa Alessandra, Mallamaci Francesca, Macrì Roberta, Pisano Anna, Spoto Belinda, Malatino Lorenzo S, Stancanelli Benedetta, Tripepi Giovanni, Benedetto Francesco A, Zoccali Carmine
Abstract excerpt
BACKGROUND: Neuropeptide Y (NPY) is a sympathetic neurotransmitter that acts on multiple receptors involved in cardiovascular remodelling and angiogenesis. Plasma levels of NPY are increased in patients with end-stage renal disease (ESRD) and are independently related to left ventricular hypertrophy (LVH) and incident cardiovascular events in these patients. OBJECTIVE: To investigate the relationship between NPY...
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