Article
Vitamin D receptor gene polymorphism and left ventricular hypertrophy in chronic kidney disease.
Nutrients - 10 Mar 2014
Santoro Domenico, Gagliostro Giorgia, Alibrandi Angela, Ientile Riccardo, Bellinghieri Guido, Savica Vincenzo, Buemi Michele, Caccamo Daniela
Abstract excerpt
FokI and BsmI polymorphisms of vitamin D receptor (VDR) gene are regarded as reliable markers of disturbed vitamin D signaling pathway. Left ventricular hypertrophy (LVH) is a strong cardiovascular risk marker in end stage renal disease (ESRD) patients. Since BsmI polymorphism has been associated with LVH in ESRD patients, we addressed this study in patients with chronic kidney disease (CKD) not yet on dialysis....
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