Article
Genetic diversity of noroviruses in Chinese adults: potential recombination hotspots and GII-4/Den Haag-specific mutations at a putative epitope.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2011
Jin Miao, Chen Jinan, Zhang Xiao-Hong, Zhang Ming, Li Hui-Ying, Cheng Wei-Xia, Liu Na, Tan Ming, Jiang Taijiao, Duan Zhao-Jun
Abstract excerpt
Little is known about the role of noroviruses (NVs) in sporadic cases of acute gastroenteritis in adults. The GII-4 NVs are currently the globally dominant genotype with diverse genetic makeups. The mechanism(s) underlying the persistence and rapid evolution of the viruses are not yet clear. In this study we collected 547 specimens from adult of >14 years of age with acute gastroenteritis in Beijing, China from...
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