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α1 and β1 integrins enhance the homing and differentiation of cultured prostate cancer stem cells

7 Jun 2010

Abstract excerpt

CD133(+) prostate cancer stem cells (PCSCs) have recently been identified in human prostate cancer tissues. The present study reports the integrin profile of prostate cancer progenitor cells and the role of alpha(1) and beta(1) integrins in the homing and differentiation of PCSCs in vitro. PCSCs were isolated from the tissue specimens of patients with prostate cancer and the expression of surface integrins and...

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Identifiers

PMID: 20531279
DOI: 10.1038/aja.2010.20

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