Article
Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS.
Journal of acquired immune deficiency syndromes (1999) - 1 Aug 2010
Sezgin Efe, Hendrickson Sher L, Jabs Douglas A, Van Natta Mark L, Lewis Richard A, Troyer Jennifer L, O'Brien Stephen J
Abstract excerpt
Approximately 10%-15% of patients with AIDS but without ocular opportunistic infections will have a presumed neuroretinal disorder (HIV-NRD), manifested by reduced contrast sensitivity and abnormal visual fields. The loss of contrast sensitivity often is sufficient to impair reading speed. To evaluate the effect of host genetics on HIV-NRD, we explored validated AIDS restriction gene variants CCR5Delta32,...
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