Article
The GimA locus of extraintestinal pathogenic E. coli: does reductive evolution correlate with habitat and pathotype?
PloS one - 28 May 2010
Homeier Timo, Semmler Torsten, Wieler Lothar H, Ewers Christa
Abstract excerpt
IbeA (invasion of brain endothelium), which is located on a genomic island termed GimA, is involved in the pathogenesis of several extraintestinal pathogenic E. coli (ExPEC) pathotypes, including newborn meningitic E. coli (NMEC) and avian pathogenic E. coli (APEC). To unravel the phylogeny of GimA and to investigate its island character, the putative insertion locus of GimA was determined via Long Range PCR and...
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