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Article

Extraintestinal virulence is a coincidental by-product of commensalism in B2 phylogenetic group Escherichia coli strains.

Molecular biology and evolution - 1 Nov 2007

Le Gall Tony, Clermont Olivier, Gouriou Stéphanie, Picard Bertrand, Nassif Xavier, Denamur Erick, Tenaillon Olivier

Abstract excerpt

The selective pressures leading to the evolution and maintenance of virulence in the case of facultative pathogens are quite unclear. For example, Escherichia coli, a commensal of the gut of warm-blooded animals and humans, can cause severe extraintestinal diseases, such as septicemia and meningitis, which represent evolutionary dead ends for the pathogen as they are associated to rapid host death and poor...

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PMID: 17709333
DOI: 10.1093/molbev/msm172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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