Article
The dopamine D2 receptor gene and depressive and anxious symptoms in childhood: associations and evidence for gene-environment correlation and gene-environment interaction.
Psychiatric genetics - 1 Dec 2010
Hayden Elizabeth P, Klein Daniel N, Dougherty Lea R, Olino Thomas M, Laptook Rebecca S, Dyson Margaret W, Bufferd Sara J, Durbin C Emily, Sheikh Haroon I, Singh Shiva M
Abstract excerpt
OBJECTIVES: Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety. Furthermore, recent papers suggest that children with A1 allele of this gene may receive less positive parenting, and that the effects of this gene on child symptoms may be moderated by parenting. We sought to replicate and extend these findings using behavioral...
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