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Sperm DNA Integrity in Men Treated for Childhood Cancer

3 Jun 2010

Abstract excerpt

PURPOSE: It is not known whether childhood cancer and its treatment are associated with sperm DNA damage, which subsequently affects fertility and might be transmitted to the offspring. The aim of this study is to assess DNA fragmentation index (DFI) as an indicator of sperm DNA integrity in childhood cancer survivors (CCS), with treatment regimen taken into account. EXPERIMENTAL DESIGN: In 99 CCS and 193...

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PMID: 20519359
DOI: 10.1158/1078-0432.ccr-10-0140

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