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Article

Sperm DNA integrity in cancer patients before and after cytotoxic treatment

14 Jun 2010

Abstract excerpt

BACKGROUND: We assessed sperm DNA fragmentation index (DFI) in cancer patients before and after treatment to evaluate if sperm DNA integrity is compromised by cancer itself or its treatment. METHODS: In a prospective study, DFI was assessed in 127 patients diagnosed with testicular germ cell tumours (TGCT), Hodgkin's lymphoma (HL), non-Hodgkin's lymphoma (NHL) and various malignancies. The severity of cancer and...

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PMID: 20551071
DOI: 10.1093/humrep/deq104

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