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Article

Directionality of epistasis in a murine intercross population.

Genetics - 1 Aug 2010

Pavlicev Mihaela, Le Rouzic Arnaud, Cheverud James M, Wagner Günter P, Hansen Thomas F

Abstract excerpt

Directional epistasis describes a situation in which epistasis consistently increases or decreases the effect of allele substitutions, thereby affecting the amount of additive genetic variance available for selection in a given direction. This study applies a recent parameterization of directionality of epistasis to empirical data. Data stems from a QTL mapping study on an intercross between inbred mouse (Mus...

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Identifiers

PMID: 20516493
DOI: 10.1534/genetics.110.118356
PMCID: PMC2927772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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