Article
[Mutation of EGFR signaling pathway and therapy for metastatic colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 May 2010
Nozawa Keijirou, Watanabe Toshiaki
Abstract excerpt
For the patient in whom the Kras gene variation appears, cancer cell grow and continue to multiply even if blocked by EGFR inhibitor. A topping the offered figure effect of cetuximab is not accepted. The addition of cetuximab for treatment of metastatic colorectal cancer with Kras wild-type tumor...
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