Article
Association of insulin receptor genetic variants with polycystic ovary syndrome in a population of women from Central Europe.
Fertility and sterility - 1 Nov 2010
Hanzu Felicia A, Radian Serban, Attaoua Redha, Ait-El-Mkadem Samira, Fica Simona, Gheorghiu Monica, Coculescu Mihai, Grigorescu Florin
Abstract excerpt
To assess the role of the insulin receptor gene in polycystic ovary syndrome (PCOS) we performed a case-control study in a female population (n=226) from Central Europe by examining the genetic associations of single nucleotide polymorphisms (rs8107575, rs2245648, rs2245649, rs2963, rs2245655, and ) and inferred haplotypes around exon 9 of this gene. The ancestral T allele of single nucleotide polymorphism...