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Article

Validation of the GenoType MTBDRplus assay for detection of MDR-TB in a public health laboratory in Thailand.

BMC infectious diseases - 20 May 2010

Anek-Vorapong Rapeepun, Sinthuwattanawibool Chalinthorn, Podewils Laura Jean, McCarthy Kimberly, Ngamlert Keerataya, Promsarin Busakorn, Varma Jay K

Abstract excerpt

BACKGROUND: Over the past several years, new diagnostic techniques have been developed to allow for the rapid detection of multidrug resistant tuberculosis. The GenoType MTBDRplus test is a deoxyribonucleic acid (DNA) strip assay which uses polymerase chain reaction (PCR) and hybridization to detect genetic mutations in the genes that confer isoniazid (INH) and rifampn (RIF) resistance. This assay has...

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Identifiers

PMID: 20487550
DOI: 10.1186/1471-2334-10-123
PMCID: PMC2886057

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