Article
Validation of the GenoType MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam.
BMC infectious diseases - 3 Jun 2010
Huyen Mai N T, Tiemersma Edine W, Lan Nguyen T N, Cobelens Frank G J, Dung Nguyen H, Sy Dinh N, Buu Tran N, Kremer Kristin, Hang Pham T, Caws Maxine, O'Brien Richard, van Soolingen Dick
Abstract excerpt
BACKGROUND: To control multidrug resistant tuberculosis (MDR-TB), the drug susceptibility profile is needed to guide therapy. Classical drug susceptibility testing (DST) may take up to 2 to 4 months. The GenoType MTBDRplus test is a commercially available line-probe assay that rapidly detects Mycobacterium tuberculosis (MTB) complex, as well as the most common mutations associated with rifampin and isoniazid...
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