Article
Gene expression profiling identifies WNT7A as a possible candidate gene for decreased cancer risk in fragile X syndrome patients.
Archives of medical research - 1 Feb 2010
Rosales-Reynoso Mónica Alejandra, Ochoa-Hernández Alejandra Berenice, Aguilar-Lemarroy Adriana, Jave-Suárez Luis Felipe, Troyo-Sanromán Rogelio, Barros-Núñez Patricio
Abstract excerpt
BACKGROUND AND AIMS: Although sporadic cases of cancer in patients with fragile X syndrome (FXS) have been reported, extensive studies carried out in Denmark and Finland concluded that cancer incidence in these patients is lower than in the general population. On the other hand, the FMR1 protein, which is involved in the translation process, is absent in FXS patients. Hence, it is reasonable to assume that these...
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