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Article

Lentivirus-associated MAPK/ERK2 phosphorylates EMD and regulates infectivity.

The Journal of general virology - 1 Sept 2010

Bukong Terence N, Hall William W, Jacqué Jean-Marc

Abstract excerpt

Infection of a cell by lentiviruses, such as human immunodeficiency virus type 1 or feline immunodeficiency virus, results in the formation of a reverse transcription complex, the pre-integration complex (PIC), where viral DNA is synthesized. In non-dividing cells, efficient nuclear translocation of the PIC requires the presence of the inner nuclear lamina protein emerin (EMD). Here, we demonstrate that EMD...

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Identifiers

PMID: 20463147
DOI: 10.1099/vir.0.019604-0

Genes

EMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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