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Article

Inferring fitness landscapes.

Evolution; international journal of organic evolution - 1 Sept 2010

Shaw Ruth G, Geyer Charles J

Abstract excerpt

Since 1983, study of natural selection has relied heavily on multiple regression of fitness on the values for a set of traits via ordinary least squares (OLSs), as proposed by Lande and Arnold, to obtain an estimate of the quadratic relationship between fitness and the traits, the fitness surface. However, well-known statistical problems with this approach can affect inferences about selection. One key concern is...

Topics

Models, Theoretical
Phenotype
Regression Analysis
Selection, Genetic

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20456492
DOI: 10.1111/j.1558-5646.2010.01010.x

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