Article
Garcinol sensitizes human pancreatic adenocarcinoma cells to gemcitabine in association with microRNA signatures.
Molecular nutrition & food research - 1 Feb 2013
Parasramka Mansi A, Ali Shadan, Banerjee Sanjeev, Deryavoush Tara, Sarkar Fazlul H, Gupta Smitiv
Abstract excerpt
BACKGROUND: Alterations in microRNA (miRNA/miR) genes are of biological importance in the pathophysiology of cancers, including pancreatic cancer (PaCa). Although growing evidence supports the role of miRNA in cancer, their response to dietary phytochemicals is less known. Previously, we showed that garcinol induces PaCa cell growth arrest and apoptosis in vitro. The present study, discusses chemo-sensitization...
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