Article
A reduced number of mtSNPs saturates mitochondrial DNA haplotype diversity of worldwide population groups.
PloS one - 3 May 2010
Salas Antonio, Amigo Jorge
Abstract excerpt
BACKGROUND: The high levels of variation characterising the mitochondrial DNA (mtDNA) molecule are due ultimately to its high average mutation rate; moreover, mtDNA variation is deeply structured in different populations and ethnic groups. There is growing interest in selecting a reduced number of mtDNA single nucleotide polymorphisms (mtSNPs) that account for the maximum level of discrimination power in a given...
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