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Article

Isolation of a variant family of mouse minor satellite DNA that hybridizes preferentially to chromosome 4.

Genomics - 1 May 1991

Broccoli D, Trevor K T, Miller O J, Miller D A

Abstract excerpt

Two cosmids (HRS-1 and HRS-2) containing mouse minor satellite DNA sequences have been isolated from a mouse genomic library. In situ hybridization under moderate stringency conditions to metaphase chromosomes from RCS-5, a tumor cell line derived from the SJL strain, mapped both HRS-1 and HRS-2 to the centromeric region of chromosome 4. Sequence data indicate that these cloned minor satellite DNA sequences have...

Topics

Animals
Base Sequence
Blotting, Southern
Centromere
Chromosome Mapping
Cloning, Molecular
Cosmids
DNA, Satellite
Gene Library
Genetic Variation
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Repetitive Sequences, Nucleic Acid

Tumor Cells, Cultured

Source

Identifiers

PMID: 2045111
DOI: 10.1016/0888-7543(91)90485-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2045111-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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