Article
A molecular deletion of distal chromosome 4p in two families with a satellited chromosome 4 lacking the Wolf-Hirschhorn syndrome phenotype.
American journal of human genetics - 1 Nov 1992
Estabrooks L L, Lamb A N, Kirkman H N, Callanan N P, Rao K W
Abstract excerpt
We report two families with a satellited chromosome 4 short arm (4ps). Satellites and stalks normally occur on the short arms of acrocentric chromosomes; however, the literature cites several reports of satellited nonacrocentric chromosomes, which presumably result from a translocation with an ac...
Topics
- Abnormalities, Multiple
- Blotting, Southern
- Child, Preschool
- Chromosome Deletion
- Chromosomes, Human, Pair 4
- DNA, Satellite
- Developmental Disabilities
- Female
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Pedigree
- Phenotype
- Syndrome