Article
Effects of vaccination on onset and outcome of Dravet syndrome: a retrospective study.
The Lancet. Neurology - 1 Jun 2010
McIntosh Anne M, McMahon Jacinta, Dibbens Leanne M, Iona Xenia, Mulley John C, Scheffer Ingrid E, Berkovic Samuel F
Abstract excerpt
BACKGROUND: Pertussis vaccination has been alleged to cause an encephalopathy that involves seizures and subsequent intellectual disability. In a previous retrospective study, 11 of 14 patients with so-called vaccine encephalopathy had Dravet syndrome that was associated with de-novo mutations of the sodium channel gene SCN1A. In this study, we aimed to establish whether the apparent association of Dravet...
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