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Article

Evidence for DNA hairpin recognition by Zta at the Epstein-Barr virus origin of lytic replication.

Journal of virology - 1 Jul 2010

Rennekamp Andrew J, Wang Pu, Lieberman Paul M

Abstract excerpt

The Epstein-Barr virus immediate-early protein (Zta) plays an essential role in viral lytic activation and pathogenesis. Zta is a basic zipper (b-Zip) domain-containing protein that binds multiple sites in the viral origin of lytic replication (OriLyt) and is required for lytic-cycle DNA replication. We present evidence that Zta binds to a sequence-specific, imperfect DNA hairpin formed by an inverted repeat...

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Share to DNA, Viral
Share to Epstein-Barr Virus Infections
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20444899
DOI: 10.1128/JVI.02666-09
PMCID: PMC2898250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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