Article
Isotopologue profiling of Legionella pneumophila: role of serine and glucose as carbon substrates.
The Journal of biological chemistry - 16 Jul 2010
Eylert Eva, Herrmann Vroni, Jules Matthieu, Gillmaier Nadine, Lautner Monika, Buchrieser Carmen, Eisenreich Wolfgang, Heuner Klaus
Abstract excerpt
Legionella pneumophila (Lp) is commonly found in freshwater habitats but is also the causative agent of Legionnaires' disease when infecting humans. Although various virulence factors have been reported, little is known about the nutrition and the metabolism of the bacterium. Here, we report the application of isotopologue profiling for analyzing the metabolism of L. pneumophila. Cultures of Lp were supplied with...
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