Article
Inbreeding depression and outbreeding depression are evident in wild-type zebrafish lines.
Zebrafish - 1 Jun 2010
Monson Christopher A, Sadler Kirsten C
Abstract excerpt
Maintaining wild-type (WT) zebrafish stocks for research while preserving viability within the lines used presents significant challenges to zebrafish husbandry practices. Genetic homogeneity is established through inbreeding to provide continuity across experiments. This, however, leads to decreased fitness through inbreeding depression. In the laboratory setting, it is imperative that researchers consistently...
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