Article
Age and sex dependent genetic effects of neuropeptide Y promoter polymorphism on susceptibility to ischemic stroke in Koreans.
Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010
Kim No S, Ko Mi M, Cha Min H, Oh Se-Mi, Bang Ok S
Abstract excerpt
BACKGROUND: In our previous study, the neuropeptide Y (NPY) C-399T promoter polymorphism (rs16147C>T) was identified as a risk factor for ischemic stroke in Koreans. In this study, we investigated whether age and sex modify the genetic effect of C-399T on susceptibility to ischemic stroke. METHODS: A total of 1,350 subjects (802 ischemic stroke patients, 548 healthy controls) were genotyped for C-399T using a...
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