Article
Linking MECP2 and pain sensitivity: the example of Rett syndrome.
American journal of medical genetics. Part A - 1 May 2010
Downs Jenny, Géranton Sandrine M, Bebbington Ami, Jacoby Peter, Bahi-Buisson Nadia, Ravine David, Leonard Helen
Abstract excerpt
Recent animal studies suggest links between MeCP2 function and sensitivity to pain. This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. Families enrolled in the Australian Rett Syndrome Database (ARSD) and InterRett database participated in this study. Cases with a known MECP2 pathogenic mutation, whose families had...
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