Article
Cholestatic liver disease in children.
Current gastroenterology reports - 1 Feb 2010
Santos Jorge L, Choquette Monique, Bezerra Jorge A
Abstract excerpt
Inherited syndromes of intrahepatic cholestasis and biliary atresia are the most common causes of chronic liver disease and the prime indication for liver transplantation in children. Our understanding of the pathogenesis of these diseases has increased substantially by the discovery of genetic mutations in children with intrahepatic cholestasis and the findings that inflammatory circuits are operative at the...
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