Article
Frequent inactivation of hSRBC in ovarian cancers by promoter CpG island hypermethylation.
Acta obstetricia et gynecologica Scandinavica - 1 May 2010
Tong Seo-Yun, Ki Kyung-Do, Lee Jong-Min, Kang Min-Ju, Ha Tae-Kyu, Chung Seong-In, Chi Sung-Gil, Lee Seon-Kyung
Abstract excerpt
OBJECTIVE: To explore the implication of human SRBC gene [serum deprivation response factor-related gene product that binds to the c-kinase (hSRBC)] abnormality in ovarian tumorigenesis. DESIGN: Retrospective study. SETTING: Medical center. SAMPLE: Twenty-two epithelial ovarian cancer and six normal ovary tissues. MEASURES: Mutation and altered expression of hSRBC gene. METHODS: hSRBC expression was characterized...
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