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Article

c-MET pathway involvement in chronic rhinosinusitis: a genetic association analysis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 May 2010

Castano Roberto, Bossé Yohan, Endam Leandra Mfuna, Filali-Mouhim Abdelali, Desrosiers Martin

Abstract excerpt

OBJECTIVE: The c-MET receptor and its ligand hepatocyte growth factor (HGF) has been shown to be overexpressed in tissue from chronic rhinosinusitis (CRS) patients with nasal polyps compared with that from controls. We assessed the genetic association of polymorphisms in the met proto-oncogene (MET) gene with CRS. STUDY DESIGN: Case-control genetic association study. SETTING: Tertiary-care university hospital....

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Source

Identifiers

PMID: 20416453
DOI: 10.1016/j.otohns.2010.01.004

Genes

MET
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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