Article
The effect of nutrition during early life on the epigenetic regulation of transcription and implications for human diseases.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2011
Lillycrop Karen A, Burdge Graham C
Abstract excerpt
Epigenetic processes which include DNA methylation, histone modification and miRNAs are integral in determining when and where specific genes are expressed. There is now increasing evidence that the epigenome is susceptible to a variety of environmental cues, such as nutrition, during specific periods of development. The changes induced by early-life nutrition may reflect an adaptive response of the foetus to...
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