Article
Helicase ATPase activity of the Tobacco mosaic virus 126-kDa protein modulates replicase complex assembly.
Virology - 5 Jul 2010
Wang Xiao, Kelman Zvi, Culver James N
Abstract excerpt
Mutations disrupting helicase domain motifs of the Tobacco mosaic virus 126/183-kDa proteins were investigated for their effect on replicase function and assembly. These mutations inhibited virus replication but did not affect 126-kDa induced N gene resistance or RNAi suppression. However, in vivo expressed 126-kDa motif mutants yielded two distinct cytoplasmic phenotypes that correlated with ATPase activity....
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