Article
NEMO mutation as a cause of familial occurrence of Behçet's disease in female patients.
Clinical genetics - 1 Dec 2010
Takada H, Nomura A, Ishimura M, Ichiyama M, Ohga S, Hara T
Abstract excerpt
Behçet's disease is a chronic, relapsing, multisystem inflammatory disease of unknown etiology. Nuclear factor κB (NF-κB) essential modulator (NEMO) that is required for the activation of NF-κB plays an important role in inflammation. To investigate the role of NEMO in the pathogenesis of Behçet's disease, we analyzed NEMO gene and its expression pattern in tissues in a family with Behçet's disease. We found a...
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