Article
Impact of Pseudomonas aeruginosa genomic instability on the application of typing methods for chronic cystic fibrosis infections.
Journal of clinical microbiology - 1 Jun 2010
Fothergill Joanne L, White Judith, Foweraker Juliet E, Walshaw Martin J, Ledson Martin J, Mahenthiralingam Eshwar, Winstanley Craig
Abstract excerpt
The Liverpool epidemic strain (LES) of Pseudomonas aeruginosa is widespread among cystic fibrosis (CF) patients in the United Kingdom and has emerged recently in North America. In this study, we report the analysis of 24 "anomalous" CF isolates of P. aeruginosa that produced inconsistent results with regard to either pulsed-field gel electrophoresis (PFGE) or PCR tests for the LES. We used a new typing method,...
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