Article
Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells.
Tissue engineering. Part A - 1 Jul 2010
Little Dianne, Guilak Farshid, Ruch David S
Abstract excerpt
Human adipose stem cells (hASCs) can differentiate into a variety of phenotypes. Native extracellular matrix (e.g., demineralized bone matrix or small intestinal submucosa) can influence the growth and differentiation of stem cells. The hypothesis of this study was that a novel ligament-derived matrix (LDM) would enhance expression of a ligamentous phenotype in hASCs compared to collagen gel alone. LDM prepared...
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