Article
Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering.
Biomaterials - 1 Jan 2011
Colazzo Francesca, Sarathchandra Padmini, Smolenski Ryszard T, Chester Adrian H, Tseng Yuan-Tsan, Czernuszka Jan T, Yacoub Magdi H, Taylor Patricia M
Abstract excerpt
A key challenge in tissue engineering a heart valve is to reproduce the major tissue structures responsible for native valve function. Here we evaluated human adipose-derived stem cells (ADSCs) as a source of cells for heart valve tissue engineering investigating their ability to synthesize and process collagen and elastin. ADSCs were compared with human bone marrow mesenchymal stem cells (BmMSCs) and human...
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