Article
The vascular endothelial growth factor-2549 insertion/deletion polymorphism is not associated with susceptibility to hepatocellular carcinoma in Chinese.
DNA and cell biology - 1 Jul 2010
He Yan, Ni Jianqiang, Chen Shougong, Jiang Yuting, Jia Shasha, Gao Yuzhen
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis, which is crucial for development and metastasis of tumors including hepatocellular carcinoma (HCC), and elevated VEGF levels in serum and tissues have been known to be related with poor prognosis in patients with HCC. Polymorphisms in VEGF may alter VEGF protein concentrations, influence the process of angiogenesis, and may relate to...
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