Article
Non-synonymous polymorphism in the neuropeptide S precursor gene and sleep apnea.
Sleep & breathing = Schlaf & Atmung - 1 Sept 2011
Sánchez-de-la-Torre Manuel, Pierola Javier, Vidal Carme, Barceló Antonia, de la Peña Mónica, Hussain Zahid, Capote Francisco, Durán Joaquín, Agustí Alvar G N, de Lecea Luis, Torres Gerard, Esquinas Cristina, Martinez Montserrat, Barbé Ferran
Abstract excerpt
BACKGROUND: Obstructive sleep apnea syndrome (OSAS) is a complex disease with a strong genetic basis. One of the primary molecular domains affected by OSAS is sympathetic activity. Neuropeptide S (NPS) plays an important role in the regulation of the sleep-wakefulness cycle, anxiety states, and daytime sleepiness. It is important to study neuropeptides related to sympathetic activity regulation and how their...
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