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Article

Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells

1 May 2010

Abstract excerpt

As histone deacetylase inhibitors such as romidepsin (depsipeptide, FK228) complete successful Phase I clinical trials in pediatric solid tumors, it is important that their mechanisms of action are delineated in order to inform the development of subsequent clinical trials as single agents or in combination therapies. In this study, we evaluate the effect of romidepsin as a single agent on a number of different...

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Share to Histone Deacetylase Inhibitors Research
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PMID: 20404560
DOI: 10.4161/cc.9.9.11543

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Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cellsPMID 20404560Read ↗

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