Phosphoproteome dynamics reveal heat-shock protein complexes specific to the <i>Leishmania donovani</i> infectious stage

Abstract excerpt

Leishmania is exposed to a sudden increase in environmental temperature during the infectious cycle that triggers stage differentiation and adapts the parasite phenotype to intracellular survival in the mammalian host. The absence of classical promoter-dependent mechanisms of gene regulation and constitutive expression of most of the heat-shock proteins (HSPs) in these human pathogens raise important unresolved...

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