Article
Dissociable influences of NR2B-receptor related neural transmission on functions of distinct associative basal ganglia circuits.
NeuroImage - 1 Aug 2010
Beste Christian, Baune Bernhard T, Domschke Katharina, Falkenstein Michael, Konrad Carsten
Abstract excerpt
Glutamate is an important excitatory neurotransmitter within functional prefrontal-basal ganglia loops. These distinct loops mediate different cognitive functions. One function of the anterior-cingulate loop is error processing. One function of the orbito-frontal loop is response inhibition. These functions are altered in several neuro-psychiatric disorders like Huntington's disease (HD). Because of the known...
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