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Biomarkers in Alzheimer's Disease: Past, Present and Future

1 Feb 2010

Abstract excerpt

Epidemiological and molecular studies suggest that Alzheimer's disease (AD) has multiple etiologies including genetic mutations, genetic variations affecting susceptibility and environmental factors. These aspects can promote the formation and accumulation of insoluble amyloid-beta and hyperphosphorylated tau. Since the disease is multifactorial and clinical diagnosis is highly exclusive, the need for a...

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PMID: 20387301
DOI: 10.2217/bmm.09.86

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