Article
Molecular determinants of the cardiometabolic phenotype.
Endocrine, metabolic & immune disorders drug targets - 1 Jun 2010
de las Fuentes Lisa, de Simone Giovanni, Arnett Donna K, Dávila-Román Víctor G
Abstract excerpt
The metabolic syndrome represents a clustering of risk factors that has been shown to predict adverse cardiovascular outcomes. Although the precise mechanisms contributing to the cardiometabolic syndrome (CMS) remain poorly defined, accumulating evidence identifies two intersecting candidate pathways responsible for inflammation and energy homeostasis in the pathophysiology that underlie cardiometabolic traits....
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