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Article

T-cell leukemia 1 expression in nodal Epstein-Barr virus-negative diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma.

Human pathology - 1 Sept 2010

Gualco Gabriela, Weiss Lawrence M, Barber Glen N, Bacchi Carlos E

Abstract excerpt

The physiologic expression of the product of the proto-oncogene TCL1 (T-cell leukemia 1) is primarily restricted to early embryonic cells. In nonneoplastic B cells, the expression of TCL1 is determined by the differentiation step with silencing at the germinal center stage. TCL1 protein is overexpressed in a wide variety of human diseases. It has been shown that TCL1 is a powerful B-cell oncogene, which has been...

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Share to Epstein-Barr Virus Infections
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell

Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 20382409
DOI: 10.1016/j.humpath.2010.01.015

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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