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Article

The CYP1A1 Ile462Val polymorphism and platinum resistance of epithelial ovarian neoplasms.

Oncology research - 1 Jan 2010

Heubner Martin, Wimberger Pauline, Riemann Kathrin, Kasimir-Bauer Sabine, Otterbach Friedrich, Kimmig Rainer, Siffert Winfried

Abstract excerpt

The role of estrogens in ovarian carcinogenesis and progression of ovarian cancer is unclear. Cytochrome P450 is involved in estrogen metabolism, and polymorphisms have been associated with functional changes and risk for ovarian cancer. In this study, we investigated the impact of the CYP1A1 Ile...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20377136
DOI: 10.3727/096504010x12626118079903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20377136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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