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Article

‘Genetic profiling’ and ovarian cancer therapy (Review)

17 Jun 2011

Abstract excerpt

High variability observed among ovarian cancer patients in response to the same therapy and the related toxicity may be correlated to gene polymorphisms and genetic alterations affecting the metabolism of drugs commonly used to treat this tumor. Recent studies have shown a correlation between the polymorphisms characterizing GSTM1-T1 detoxifying enzymes and poor outcome in advanced ovarian cancer patients treated...

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PMID: 21687948
DOI: 10.3892/mmr.2011.512

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