Article
Molecular Variants of HPV Type 16 E6 Among Honduran Women.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Apr 2010
Tabora Nelba, Melchers Willem J G, van Doorn Leen-Jan, Quint Wim, Ferrera Annabelle
Abstract excerpt
OBJECTIVE: In this study, we investigated the prevalence of human papillomavirus 16 (HPV-16) variants in Honduran women with normal cytology and with dysplasia and cervical cancer. METHODS: Samples identified as positive for HPV-16 by SPF10-LiPA were tested for intratypic subtypes and variants by analysis of the E6/E7 region using a novel reverse hybridization assay (line probe assay). RESULTS: We found that most...
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