Article
Balanced electrostatic and structural forces guide the large conformational change associated with maturation of T = 4 virus.
Biophysical journal - 7 Apr 2010
Matsui Tsutomu, Tsuruta Hiro, Johnson John E
Abstract excerpt
Nudaurelia capensis omega virus has a well-characterized T = 4 capsid that undergoes a pH-dependent large conformational changes (LCC) and associated auto-catalytic cleavage of the subunit. We examined previously the particle size at different pH values and showed that maturation occurred at pH 5.5. We now characterized the LCC with time-resolved small-angle x-ray scattering and showed that there were three...
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